Learn about Acthar

Acthar is an FDA-approved prescription medicine for treating lupus

Acthar is used to treat flares and on a regular basis to help manage lupus symptoms. It contains a highly purified, naturally occurring hormone called ACTH (adrenocorticotropic hormone), which is thought to play a role in the body’s immune system and its response to inflammation. Acthar is not a steroid.

Why consider
Acthar for my lupus?


  • FDA approved to treat lupus flares and for use on a regular basis (maintenance)
  • A treatment that has been used in other inflammatory and autoimmune diseases such as rheumatoid arthritis and psoriatic arthritis.

What do I need to
know about Acthar?

Acthar may not be suitable for all lupus patients.

While taking Acthar, tell your doctor if you have any of these symptoms:
Infections; adrenal gland changes; increased blood pressure, body salt and fluid levels; unpredictable response to vaccines; stomach or intestinal problems; changes in mood or behavior; worsening of other medical conditions; eye problems; or allergic reactions. Tell your doctor about any health problems or any other medicines you are taking.

How Acthar is
thought to work

Acthar is believed to work differently than other lupus medicines. It is thought to work by helping your body produce its own natural steroid hormones (such as cortisol), which help your body defend itself against inflammation and help regulate your immune system.

Although the exact way Acthar works in the body is not completely understood, more research is being conducted. This information is based on nonclinical data where the relationship to clinical benefit is not known.

Important Safety Information

Who should  NOT take Acthar?

You should not take Acthar if you have: