Lupus flares and symptoms can vary

Where does lupus affect my body?

The physical symptoms of lupus can come and go. Most people experience periods of more active disease, called flares (when symptoms worsen and you feel sick) and periods of remission (when symptoms improve and you feel better).

Symptoms of lupus can vary among patients. They can be mild or more serious, and can affect many parts of the body including:

Brain and nervous system

  • Extreme tiredness
  • Headaches
  • Fever

Nose and mouth

  • Nose and mouth sores
  • Dry mouth

Heart and lungs

  • Heart disease
  • Pain in chest with deep breathing


  • Low red blood cell counts
  • Low white blood cell counts
  • Blood clotting
  • Other abnormal blood tests


  • Butterfly-shaped rash across cheeks and nose
  • Sensitivity to sun or light
  • Hair loss
  • Fingers turning white or blue when cold


  • Kidney disease
  • Fluid retention and swelling in feet, legs, hands or around eyes

Joints and muscles

  • Painful or swollen joints
  • Muscle pain

Did You Know?

Lupus affects 10 times as many women as men. Children and teenagers can also develop lupus.

Did You Know?

People of all races and ethnic groups can develop lupus, although women of color are 2 to 3 times more likely to develop lupus than Caucasians.

Important Safety Information

Who should  NOT take Acthar?

You should not take Acthar if you have: